- Study of chemical composition of Phyllanthus cochinchinensis and Phyllanthus reticulatus.
 -  Evaluation of anti-inflammatory and antimicrobial effects of isolated compounds.

- The structure of 11 compounds (PC1-PC11) has been isolated and determined from aerial part of P. cochinchinensi species. Among the isolated compounds were 4 new compounds: phyllancoside A (PC1), phyllancoside B (PC2), phyllancochine A (PC3) and phyllancochine B (PC4) and 11 known compounds: (PC5), 2-[4-[2,3-Dihydro-3-(hydroxymethyl)-5-(3-hydroxypropyl)-7-methoxy-2-benzofuranyl]-2,6-dimethoxyphenoxy]-1-(4-hydroxy-3-methoxyphenyl)-1,3-propanediol (PC6), acernikol (PC7), restrojusticidin B (PC8), justicidin B (PC9), dehydroguaiaretic acid (PC10), caliislignan A (PC11).
- The structure of 12 compounds (PR1-PR12) has been isolated and determined from the aerial part of P. reticulatus species. Among the isolated compounds were 2 new compounds: phyllanretioside A (PR1) and phyllanretioside B (PR2)] and 10 known compounds: corilagin (PR3), phyllanthusiin C (PR4), quercetin-3-O-β-D-glucuronopyranoside (PR5), isoquercitrin (PR6), astragalin (PR7), isohemiphloin (PR8), keampferol-3-O-rutinoside (PR9), pinoresinol (PR10), pinoresinol 4-O-β-D-glucopyranoside (PR11), (+)-isolariciresinol (PR12).
- All isolated compounds were evaluated for anti-inflammatory activity via inhibition of NO production. The results showed that phyllanthusiin C (PR4) exhibited strong NO production inhibitory activity with IC50 = 5.6 ± 0.2 (µM), stronger than the positive control in the test, dexamethasone. Compounds PC1, PC3, PC4, PC8, PC9, PR1, PR3, PR5 exhibited moderate NO inhibitory activity with IC50 values ranging from 36.6 to 94.7 (µM). 
- All isolated compounds were evaluated for antimicrobial activity. Compounds PC3, PC4 and PC10 exhibited activity against three Gram (+) strains, E. faecalis, S. aureus and B. cereus, with MIC values ranging from 32–256μg/ml. Compound PC11 inhibited two Gram (+) strains, E. faecalis and B. cereus. Except for compound PC10, the remaining compounds did not inhibit the yeast C. albicans. Compounds PR1 and PR4 inhibited most of the tested strains, while the remaining compounds inhibited 4/7 of the tested strains with MIC values ranging from 16~256 µg/ml.

- Four new compounds [phyllancoside A (PC1), phyllancoside B (PC2), phyllancochine A (PC3) and phyllancochine B (PC4)] were isolated and their structures were determined from the stems and leaves of P. cochinchinensis.
- Two new compounds [phyllanretioside A (PR1) and phyllanretioside B (PR2)] were isolated and structurally characterized from the leaves and stems of P. reticulatus.

 Compound PR4 showed good anti-inflammatory and antimicrobial activities. Therefore, this compound needs to be studied further at the in vivo level and included in the list of candidate compounds with NO production inhibition and antimicrobial effects.