- Collaborate with French partners in researching and searching for compounds with anti-microbial activity from selected strains of marine microorganisms in the Central Coast of Vietnam.
- Improve research capacity for young officials participating in the mission.
- Building sustainable scientific cooperation and expanding scientific cooperation in the direction of researching biologically active natural compounds and testing biological effects.

The mission researched and discovered antimicrobial secondary metabolites from some selected strains of microorganisms in the Central Coast of Vietnam. In the framework of cooperation with France, the mission completed the proposed objectives, including:  searching for antimicrobial compounds from some selected strains of marine microorganisms in Vietnam; improving research capacity for young staff participating in mission; building sustainable scientific cooperation relationships and expanding scientific cooperation in the field of researching bioactive natural products and their bioactivity evaluation. Below are the detailed results of the mission:
Activated and cultured in small scale of 500 mL of 7 microorganism strains, to obtain the respective extracts and they were screened for anti-microbial activity. The results showed that all 7 strains were active against 2 to 6 tested strains out of 7 strains. Accordingly, G222, G810 and M852 are the most active ones.
Streptomyces sp. G222 and Aspergillus versicolor M852 were selected to identify and cultured in large scale of 50 liters for further chemical constituents’ studies.
Isolated and determined structures of 10 compounds from the strain Aspergillus M852. The isolated compounds are alkaloids, cyclic peptides, phenolic compounds, which are consistent with the data of genus Aspergillus.
The isolated compounds were tested for the antimicrobial activity. As a result, compounds M852-1, M852-2, M852-3, M852-6 and M852-9 exhibited the antimicrobial activity against some tested microorganisms.
The results of the mission created a premise for the two sides to enhance the cooperation in the field of research of bioactive compounds from marine microorganism.

Activated and screened for the antimicrobial activity of the extracts of 7 isolated strains of microorganisms. Two strains of highly active microorganisms have been identified. Streptomyces sp. G222 and Aspergillus versicolor M852 were selected to identify and cultured in large scale of 50 liters for further chemical constituents’ studies.
Isolated and determined structures of 10 compounds from the strain Aspergillus M852. The isolated compounds are alkaloids, cyclic peptides, phenolic compounds, which are consistent with the data of genus Aspergillus.
The isolated compounds were tested for the antimicrobial activity. As a result, compounds M852-1, M852-2, M852-3, M852-6 and M852-9 exhibited the antimicrobial activity against some tested microorganisms.

Enhance the cooperation with the National Museum of Natural History (France) in the field of bioorganic chemistry and chemistry of secondary metabolites from marine microorganism.