Project's information
Project's title | Identification of anti-lung cancer phytochemicals from the genus Vitex in Vietnam |
Project’s code | QTKR01.01/22-23 |
Research hosting institution | Institute of Marine Biochemistry (IMBC) |
Coordinating unit, co-chair | National Research Foundation of Korea |
Project leader’s name | PhD. Phan Thi Thanh Huong and PhD. SeonJu Park |
Project duration | 01/01/2022 - 30/06/2024 |
Project’s budget | 200 million VND |
Classify | Excellent |
Goal and objectives of the project | -Isolation and identification of anti-lung cancer constitutents from the genus Vitex growing in Vietnam |
Main results | -Preparation of methanol extract and screening anti-lung cancer activity of 3 Vitex species including Vitex trifolia L., Vitex trifolia subsp. litoralis Steenis and Vitex limonifolia Wall.. Based on screening results, the fruits of V.trifolia was selected for further investigation. |
Novelty and actuality and scientific meaningfulness of the results | -Isolation and determination of three previously undescribed compounds and two compounds have cytotoxic effects on PC9 cells with IC50 of 5.36 and 11.42 µM |
Products of the project | - Publications: 01 SCIE indexed journal |
Recommendations | - Futher study on chemical constitutents of V. trifolia and other popular Vitex species in Vietnam should be done to identify good biological activity agents. |
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