Project's information

Project's title Application study of sensors based on semiconducting carbon nanotube for the evaluation of the activities of ion channels on living cells
Project’s code GUST.STS.ĐT2020-CH02
Research hosting institution Graduate University of Science and Technology
Project leader’s name Pham Ba Viet Anh
Project duration 01/09/2020 - 30/09/2022
Project’s budget 300 million VND
Classify Fair
Goal and objectives of the project

- Overview of fabrication methods for field-effect transistors based on semiconducting carbon nanotubes and their application in biomedical chemistry research.
- Investigation of properties such as dimensions, surface characteristics, electrical characteristics.
- Application of the device to monitor the activity of ion channels on living cells and evaluate the influence of some stimulants on the ion channel activity.
- Publication of research results in domestic and international specialized journals.

Main results

- Summarizing issues related to the research content of the topic such as manufacturing methods and applications of field-effect transistors; study methods of ion channels on living cells.
- Investigating the characteristics of field-effect transistor sensors based on carbon nanotubes.
- Applying carbon nanotube transisors to evaluate the influence of histamine and chlorpheniramine on the activity of Ca2+ ion flux on Hela cells.

Novelty and actuality and scientific meaningfulness of the results

- The results of the project can be used in the development and application of CNT-FET semiconducting sensors in biomedical chemistry research.
- The reports and research results of the project are a valuable reference source for students and researchers at Graduate University of Science and Technology.
- The project will be the basis for proposing new research related to biomedical chemical sensors.

Products of the project

- Scientific papers in referred journals (list):
1. Viet Anh Pham Ba; Ngoc Pham Van Bach; Thien Nguyen Luong; Khoa Viet Nguyen. Semiconducting Carbon Nanotube-Based Nanodevices for Monitoring the Effects of Chlorphenamine on the Activities of Intracellular Ca2+ Stores. Journal of Analytical Methods in Chemistry 2022, 2022, 9019262.
2. Viet Anh Pham Ba; Ngoc Pham Van Bach; Khoa Viet Nguyen. Monitoring of Histamine-Induced Calcium Channel Activity of a Single Cell Using Semiconducting Carbon Nanotube Transistors. Vietnam Journal of Science and Technology 2022. (accepted)
- Patents (list): No
- Technological products (describe in details: technical characteristics, place):
+ Final report of research results of the project: 01
+ Summary report of research results in Vietnamese: 01
+ Summary report of research results in English: 01
+ Research article in SCIE journal: 01
+ Research article in VAST 2 journal: 01

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