The objective of the project is to give the structure of fucoidans that are extracted from some brown algae, and to study the radiosensitizing activity of natural fucoidan and their modified derivatives products for  drugs and supplements preparation that support for cancer treatment.

The results of the study have provided data on the structure and radiosensitizing activity of fucoidan extracted from seaweed species of the family Sargassaceae. The results added to the collection of marine microorganisms of 35 strains of marine bacteria isolated from sponges collected in Khanh Hoa and Binh Thuan sea. Preliminarily determined the catalytic properties of enzymes extracted from selected marine bacteria strain with high activity on fucoidan substrates from S. oligocystum.

- Publications:
SCIE Journal: 01
An O Zueva, A S Silchenko, A B Rasin, M I Kusaykin, R V Usoltseva, A I Kalinovsky, V V Kurilenko, T N Zvyagintseva, P D Thinh, S P Ermakova, 2020.  Expression and biochemical characterization of two recombinant fucoidanases from the marine bacterium Wenyingzhuangia fucanilytica CZ1127 T. Int J Biol Macromol, 164:3025-3037, doi: 10.1016/j.ijbiomac.2020.08.131.
VAST2 Journals: 01
Lê Đỗ Thùy Vi, Bùi Văn Nguyên, Lê Công Hoan, Trần Thị Thanh Vân, Võ Thành Trung, Phạm Trung Sản, Phạm Đức Thịnh, 2019. Thành phần và đặc điểm cấu trúc của polysaccharide sulfate tách từ rong nâu Sargassum oligocysctum ở Việt Nam. Tạp chí Hóa học, 57 (4e1,2) 60-64.
Education: The project has supported the training of 02 Masters in Chemistry

Conclusion: This project was carried out in 2019-2021 and completed the research contents on schedule.
Suggestion: It is necessary to continue to expand the research of biologically active substances from Vietnamese marine organisms in order to exploit and rationally use natural resources