Isolation and identification of fungal strains contaminated in soybean, peanut, corn, sesame and their mycotoxin products.

- Isolation, fermentation, and creation of extracts of 40 fungal strains contaminated in soybean, peanut, corn, and sesame and 11 market products with ingredients of soybean, peanut, corn, and sesame.
- Taxonomic identification of 12 isolated fungal strains.
- Isolation and structural elucidation of 47 compounds, including eight mycotoxins from six fungal strains.
- Evaluation of antimicrobial effects of the extracts of the isolated fungal strains and compounds.
- Evaluation of cytotoxicity of the extracts of the isolated fungal strains and compounds.
- Evaluation of nitric oxide inhibitory effects of 24 compounds isolated from the fungal strains NML01 and NMDT01.
- Development of eight processes for identification of eight mycotoxins produced by the fungal strains.
- Application of the processes in identification of eight mycotoxins in the fungal strains and market products stored improperly and of poor quality.

- Isolation and structural elucidation of five new compounds and two new natural compounds.
- Evaluation of antimicrobial effects of several compounds for the first time.
- Evaluation of cytotoxic effects of several compounds for the first time.
- Evaluation of nitric oxide inhibitory effects of several compounds for the first time.
- Identification of eight mycotoxins in molds contaminated in soybean, peanut, corn, and sesame collected in Vietnam for the first time.

- Scientific papers in referred journals (list):
+ 1st SCIE article: T.H. Quang, N.V. Phong, L.N. Anh, T.T.H. Hanh, N.X. Cuong, N.T.T. Ngan, N.Q. Trung, N.H. Nam, C.V. Minh, Secondary metabolites from a peanut-associated fungus Aspergillus niger IMBC-NMTP01 with cytotoxic, anti-inflammatory, and antimicrobial activities, Natural Product Research https://doi.org/doi.org/10.1080/14786419.2020.1868462 (2020).
+ 2nd SCIE article: T.H. Quang, N.V. Phong, D.V. Anh, T.T.H. Hanh, N.X. Cuong, N.T.T. Ngan, N.Q. Trung, H. Oh, N.H. Nam, C.V. Minh, Bioactive secondary metabolites from a soybean-derived fungus Aspergillus versicolor IMBC-NMTP02, Phytochemistry Letters 45 (2021) 93-99.
+ VAST1 article: T.H. Quang, L.N. Anh, T.T.H. Hanh, N.X. Cuong, N.T.T. Ngan, N.Q. Trung, N.H. Nam, Cytotoxic and antimicrobial benzodiazepine and phenolic metabolites from Aspergillus ostianus IMBC-NMTP03, Vietnam Journal of Chemistry 59 (2021) 660-666.
- Technological products (describe in details: technical characteristics, place):
+ 01 report on isolation, fermenation, extraction of the fungal strains contaminated in soybean, corn, peanut, and sesame. Place of storage: Institute of Marine Biochemistry.
+ 40 fungal strains with details of origin, morphological characteristics, color. Place of storage: Institute of Marine Biochemistry.
+ 01 report on the taxonomic identification of 12 fungal strains. Place of storage: Institute of Marine Biochemistry.
+ 06 reports on isolation and structural elucidation of compounds from 06 fungal strains (including NMR data). Place of storage: Institute of Marine Biochemistry.
+ 47 compounds ( 2 mg/compound). Place of storage: Institute of Marine Biochemistry.
+ 08 mycotoxins (( 5 mg/mycotoxin). Place of storage: Institute of Marine Biochemistry.
+ 01 report on evaluation of antimicrobial effects of the fungal extracts and compounds. Place of storage: Institute of Marine Biochemistry.
+ 01 report on evaluation of cytotoxicity of the fungal extracts and compounds. Place of storage: Institute of Marine Biochemistry.
+ 04 processes with the detailed steps of development for identification of the mycotoxins produced by the fungal strains. Place of storage: Institute of Marine Biochemistry.
+ 01 report on application of the processes in identification of the mycotoxins in the fungal strains and the market products with ingredients of soybean, peanut, corn, and sesame stored improperly and of poor quality. Place of storage: Institute of Marine Biochemistry.