|Project's title||Development of highly sensitive optical-and electrochemical-based methods for tracing diclofenac in surface water|
|Project’s code||QTCZ 01.02/20-21|
|Research hosting institution||Hanoi University of Science & Technology|
|Coordinating unit, co-chair||Institute of Analytical Chemistry|
|Project leader’s name||Dr. Vu Thi Thu|
|Project duration||01/04/2020 - 31/03/2022|
|Project’s budget||200 million VND|
|Goal and objectives of the project||
To develop electrochemical sensors based on hybrid nanostructures of carbonaceous (rGO), metal nanoparticles (i.e, AunPs) and/or conducting polymers (i.e., PEDOT) for tracing pharmaceutical residues in water (i.e., paracetamol, diclofenac).
|Main results|| |
We have demonstrated the electrochemical preparation of highly stable and uniform rGO-PEDOT:PSS/AuNPs film with high electron transfer rate for further application in detection of acetaminophene. The electrochemical reduction of graphene oxide suspension containing hydrophilic PEDOT:PSS results in a highly uniform and compact matrix which is firmly adhered to electrode surface. Gold nanoparticles were then decorated distinctly at high density on top of that matrix to provide electrocatalytic centers. The results on morphological characterization have demonstrated the uniformity of developed hybrid structures. It was found that the electron transfer rate was much enhanced (apparent transfer rate constant kapp was increased by 2640 times) on highly uniform AuNPs/rGO-PEDOT:PSS hybrid film. The as-prepared hybrid film was employed as transducing platform for electrochemical detection of acetaminophene at low concentrations (1-9 µM) and the detection limit was found to be as low as 532 nM.
|Novelty and actuality and scientific meaningfulness of the results|| |
A facile method to prepare hybrid nanostructure based on carbonaceous materials, metal nanoparticles, and conducting polymers in aqueous conditions using electrochemical approachs. A novel electrochemical sensor based on rGO-PEDOT:PSS/AuNPs for dection of acetaminophene with detection limit of 532 nM.
|Products of the project|| |
We acknowledge your supports for our exchange scientific activities with our partners at Czech Academy of Science.
|Images of project|| |