Project's information

Project's title Investigation and evaluation of the parasites and microorganisms in the sea areas of Vietnam with the aims to protect marine ecosystems and public health
Project’s code VAST.ĐA47.12/16-19
Research hosting institution Institute of Ecology and Biological Resources
Project leader’s name Assoc.Prof.Dr. Ha Duy Ngo
Project duration 01/01/2016 - 31/12/2019
Project’s budget 49,000 milion VND
Classify Fair
Goal and objectives of the project

- Investigate and evaluate the current status of harmful parasites in marine flora and fauna and microorganisms as a scientific basis for the sustainable development of marine ecosystems.
- Developing a dataset to serve the biodiversity statistics of harmful parasites, marine nematodes and marine microorganisms
- Contributing to raising awareness and understanding about marine parasites and microorganisms in warning of their harmful risks to marine life.

Main results

Theoretical results:
- The project has investigated overall parasites and microorganisms in coastal ecosystems and built a database set, sample collection of marine parasites and microorganisms in Vietnam.
- The collection of marine microorganisms: 200 strains of marine bacteria, 100 strains of marine fungi that were identified.
- Five new secondary metabolites from marine bacteria of the Vietnam’s sea (S248-1, S248-11, S248-12, S261-1 and M258-2) were identified.
- Ten compounds had cytotoxic activity; Eighteen compounds exhibited antimicrobial activity; Three compounds displayed an inhibition activity against Mycobacterium tuberculosis H37Rv.
- The number of published papers outperformed approved proposal. Contribute to the training of 8 PhDs and 10 MSc.
Applied results:
- Parasite and microorganisms data set and specimen set are the first and most complete scientific data for marine ecosystems in Vietnam. These are valuable documents that will be used for a long time in research, study and international cooperation.
- Data of cytotoxic, antimicrobial and antitubercular activity evaluation of 201 marine bacteria.

Novelty and actuality and scientific meaningfulness of the results

sequenses of marine parasites and microorganisms on GenBank;
- Discovered and published 1 new subfamily: Pseudohaploporinae subfam. n.; 3 new genus: Pseudohaploporus g. n., Parahaploporus g. n. and Novoechinorhynchus g. n.; and 32 species new to science;
- Five new secondary metabolites from marine bacteria of the Vietnam’s sea (S248-1, S248-11, S248-12, S261-1 and M258-2) were identified.
- Ten compounds had cytotoxic activity; Eighteen compounds exhibited antimicrobial activity; Three compounds displayed an inhibition activity against Mycobacterium tuberculosis H37Rv. Data of cytotoxic, antimicrobial and antitubercular activity evaluation of 201 marine bacteria.

Products of the project

- Scientific papers in referred journals (list):
+ The papers of SCI/SCIE Journals: 26 papers
+ The papers of other international Journals: 10 papers
+ The papers of national Journals: 40 papers
- Technological products (describe in details: technical characteristics, place):
1. Data set on marine parasites, Meiofauna (morphology, host, locality, location, etc…) were saved by PDF file in the research hosting institution.
Molecular biological database set of 35 species of parasites registered on GenBank (https://www.ncbi.nlm.nih.gov/nuccore/?term=).
2. Specimen set of parasites, Meiofauna include 7440 staining slides and specimens in ethanol and formaline, were stored at the Institute of Ecology and Biological Resources.
3. The collection of marine microorganisms were fixed in glyxerin and stored at the Institute of Biotechnology.
4. The collection of marine microorganisms: 200 strains of marine bacteria, 100 strains of marine fungi that were identified. The collection of marine microorganisms producing bioactive compounds: 10 marine bacteria that producing the antibiotics; 10 marine fungi that producing the antibiotics; 20 marine bacteria strains that producing marine polysaccharide modified enzymes; 10 marine fungi strains that producing marine polysaccharide modified enzymes were stored at the Nha Trang Institute of Technology Research and Application.
5. Pure compounds isolated and their spectra were stored at the Institute of Marine Biochemistry.
6. The collection of 101 strains of marine Vibrio, nitrifying bacteria, denitrifying bacteria, sulfur oxidizing bacteria and nitrogen fixing bacteria were stored at the Institute of Marine Science and Technology.
7. Three books about marine parasites, Meiofauna in Vietnam sea.

Images of project
1649836596793-20. hdngo.png