-    Fabrication of multifunctional magnetic-fluorescent drug delivery systems with nanostructures: Fe3O4 magnetic nanoparticles (an agent that increases MRI contrast and self-heating in the presence of an external magnetic field), carry drugs (Doxorubicin), attach a near-infrared fluorescence molecule (cyanine 5.5 or quantum dots) to a polymer or copolymer carrier.
-    Proven ability to kill cancer cells, ability to increase contrast in MRI, ability to generate heat for cancer hyperthermia and ability to be detected by fluorescence of the nanostructured drug delivery systems.

-    In terms of science: The project has fabricated multifunctional nano-drug delivery systems that exhibit magnetic properties, fluorescence, drug carrying and attaching near-infrared fluorescence. These drug delivery systems have been shown to kill cancer cells, increase contrast in MRI images, have hyperthermia capabilities, and can be monitored by fluorescence techniques.
-    In term of application: The project opens up the possibility of applying the diagnosis (by MRI and fluorescence techniques) in combination with the treatment (chemotherapy, thermotherapy) of cancer by the same multifunctional drug delivery system.
-    In term of raining: The project supports the training of 1 master.
-    In term of cooperation development: The project promotes the cooperation relationship between the 2 research groups of 2 institutes in Vietnam and France. The project leader on the Vietnamese side went to France for academic exchanges and implemented a number of techniques not yet available in Vietnam. Besides performing the tasks of the topic, the two research groups continue to have further cooperation such as doing exploratory tests for further studies.

-    The project has synthesized multifunctional nanosystems FADQ attaching CdTe quantum dots (QD) that fluoresce near infrared region at 710 nm.
-    The project has determined the conditions for attaching near-infrared fluorescence agent of cyanine 5.5 onto ferromagnetic nanoparticles, thereby making a multifunctional drug carrier system with cyanine 5.5.
-    The synthesized drug delivery systems are capable of fluorescence in the near- infrared region, carrying drugs, generating heat, killing cancer cells, enhancing MRI contrast and detectable by fluorescence equipment.

-    Publications:

+ Phuong Thu Ha, Thi Thu Huong Le, Thi Dieu Thuy Ung, Hai Doan Do, Bich Thuy Doan, Thi Thu Trang Mai, Hong Nam Pham, Thi My Nhung Hoang, Ke Son Phan and Thuc Quang Bui. Properties and bioeffects of magneto – near infrared nanoparticles on cancer diagnosis and treatment, 2020, New Journal of Chemistry, 44, 17277-17288, (Q1, IF = 3.591).

+ Le Thi Thu Huong, Phan Ke Son, Ung Thi Dieu Thuy, Tran Thi Lan Anh, Dong Thi Nham, Ha Phuong Thu. Factors affecting fluorescent intensity oF Fe3O4- cyanine 5.5 nanoparticles, Vietnam Journal of Science and Technology, accepted, VAST2.
-    Other products: Contributing to train 1 master