- Establish the pilot scale technological procedures to pre-treatment sulfide-Au ores, Au-bearing Sn-(W) and Sb ores using in situ isolated bacteria and and recover Au from pre-treated ores;
- Propose the biotechnological and chemical solutions on mineral resources exploration and processing in Central Highland in order to enhance economical benefit and prevent environmental polutions.

- Elucidate the mineralogical characteristics and mode of occurrences of Au in the 3 types of Au mineralization: sulfide-Au, Au-bearing Sn-(W) and Sb;
- Isolated 99 bacteria from collected samples from Central Highland. Classify, select and test 03 bacteria on pre-treatment sulfide ores;
- Establish 02 pilot scale technological procedures on pre-treatment sulfide-Au ore;
- Establish chemical procedure on recover and refine Au from bacterial pre-treated ores.

Biological is the advance and green technology that is applying in various areas. It is the first time, in situ bacteria was isolated and applying to pre-treatment Au-bearing sulfide ores. The promised results open the new orientation on mineral explorations. Since, biotechnology reduces operating cost, Au from low-grade ores and mining dump would be economically and environmentally proceeded and recovered. This technology could be expanded to recover others useful metals in further study.

Scientific papers in referred journals:
1. Ngoc Tung Quach, Can Pham-Ngoc, Thi Lien Bui, Trong Hoa Tran, Thi Phuong Ngo, Van The Nguyen, Thi Hanh Nguyen Vu, Tuan Anh Tran, Hoang Ha Chu, Quyet Tien Phi, 2021. Bioleaching potential of Indigenous Bacterial Consortia from Gold-bearing Sulfide Ore of Ta Nang Mine in Vietnam. Polish Journal of Environmental Studies.
2. Tran Tuan Anh, Pham Ngoc Can, Vu Hoang Ly, Ngo Thi Huong, Phan Đuc Le, 2021. Mineralogical characteristic and mode of occurrence of gold in Cu Jut Sb deposit, Cu Jut district, Dak Nong Province. Vietnam Journal of Geology, Series A, v. 375, p. 1-13.
3. Vu Thi Hanh Nguyen, Pham Ngoc Can, Bui Thi Lien, Quach Ngoc Ttng, Phi Quyet Tien, 2021. Isolating and screening iron oxidizing bacteria from gold ores of Tay Nguyen, Vietnam. Vietnam Journal of Geology, Series A, v. 375, p. 65-76.
Patents:
1. Pham Ngoc Can, Phi Quyet Tien, Tran Tuan Anh, Tran Trong Hoa, VuThi Hanh Nguyen, Bui Thi Lien, Nguyen Van The, Pre-treatment procedure Au-sulfide concentrate using Acidithiobacillus ferrooxidans TNG13 bacteria appying on Tra Nang gold ore.
2. Phạm Ngoc Can, Le Hong Son, Tran Tuan Anh, Phi Quyet Tien, Tran Trong Hoa, Vu Thi Hanh Nguyen, Precious metals enrichment procedure on solution from dissolution of Au-Cu-sulfide concentrate by NaCN applying on Dak Blo gold ore.
Technological products:
1. 6.52 g refined Au (Institute of Geological Sciences)
2. 03 bacteria species: Acidithiobacillus ferooxidans TNG13.1; Acidithiobacillus sp. TNG6.3; Pseudomonas sp. DBS10.3 (Institute of Biological Technology)
Other products:
1. Pre-treatment procedure for Au-sulfide concentrate and tailing using bacterias at pilot scale
2. Procedure on Au recovery from bacteria pre-treated ore at pilot scale.