Project's information

Project's title Study on the chemical composition and biological activity of some medicinal plants being circulated and used popularly in Hanoi market, stage 1.
Project’s code KHCBHH.02/18-20
Research hosting institution Institute of Marine Biochemistry (IMBC)
Project leader’s name Dr. Tran Thi Hong Hanh
Project duration 01/01/2018 - 31/12/2020
Project’s budget 1.500.000.000 VND
Classify Excellent
Goal and objectives of the project

- Isolation of compounds from five medicinal plants.
- Identification of structures of compounds isolated from the five medicinal plants.
- Study on anti-inflammatory and α-glucosidase inhibitory of the isolated compounds.

 
Main results

-    Theoretical results:
+ Isolation and structural identification of 67 compounds from 5 medicinal plants.
+ Preliminary assessment of the composition of some compounds isolated from 5 medicinal plants with corresponding medicinal sample purchased on the market.

 
Novelty and actuality and scientific meaningfulness of the results

Isolation and structural identification of 8 new compounds from 04 medicinal plants.
Products of the project

- Scientific papers in referred journals: published 04 SCI/SCIE
ISI papers
+ Tran Thi Hong Hanh, Pham Thi Cham, Nguyen Thi Thuy My, Nguyen The Cuong, Nguyen Hai Dang, Tran Hong Quang, Tran Thu Huong, Nguyen Xuan Cuong, Nguyen Hoai Nam & Chau Van Minh. Sesquiterpenoids from Saussurea costus. Natural Product Research 2019 Aug 12:1-7. DOI: 10.1080/14786419.2019.1650357
+ Nguyen Thi Thuy My, Tran Thi Hong Hanh, Pham Thi Cham, Nguyen Xuan Cuong, Tran Thu Huong, Tran Hong Quang, Nguyen Hoai Nam, Chau Van Minh. Andropaniosides A and B, two new ent-labdane diterpenoid glucosides from Andrographis paniculata. Phytochemistry Letters, Volume 35, February 2020, Pages 37-40
+ Hanh TTH, My NTT, Cham PT, Quang TH, Cuong NX, Huong TT, Nam NH, Minh CV. Diterpenoids and Flavonoids from Andrographis paniculata. Chem. Pharm. Bull. 68(1) 96-99, 2020
+ Tran Thi Hong Hanh, Pham Thi Cham, Hoang Anh Do, Nguyen The Cuong, Hyuncheol Oh, Tran Hong Quang, Nguyen Xuan Cuong, Nguyen Hoai Nam, Chau Van Minh. Iridoid glucosides and phenylethanoid glycosides from Plantago major. Phytochemistry Letters Vol. 39, 111-115, 2020