Theoretical results: + From the root of Luvunga scandens (Roxb). Buch. Ham, twenty two compounds, including one new limonoid, Luvunga A (17) and one new alkaloid, Luvungaside A (22), together with twenty known compounds: (E)-sinapinaldehyde (1), p-hydroxycinamaldehyde (2), protocatechuic aldehyde (3), protocatechuic acid (4), ostruthin (5), 6-geranyl-7-hydroxy-8-methoxycoumarin (6), bergapten (7), scopoletin (8), R-peucedanol (9), Xanthoarnol (10), acid umbelliferone-6-carboxylic (11), esculin (12), haploperoside (13), [(E)-3-(2,2-dimetyl-2H-chromen-6-yl) prop-2-enal (14), khellol glucoside (15), liomonin (16) và 3-O--D-glucopyranosylstigmast-5,22(E)-dien (18), 1,3-dihydroxy-2-methoxy-10-methyl-9-acridone (19), arborinin (20), 1-hydroxy-3-methoxy-10-methyl-9-acridone (21), were isolated by various chromatography methods. Among them, 6, 9, 10, 12, 13, 15 were found for the first time from the genus Luvunga, 1, 2, 3, 4,7, 8, 14 were reported for the first time from the species L. scandes. + The CHCl3, EtOAc, EtOH extracts and eleven compounds were tested their hepatoprotective effect and showed hepatoprotective activity against CCl4-induced hepatotoxicity on HepG2 cells (with prevention percentage of 20-195 %). + Preparations expressed hepatoprotective effect were constructed the extracted process. + Hepatoprotective activity in HepG2 human hepatoma cell line of preparations were evaluated by MTT assay. At the dose of 1.6g/kg decreased MDA, ALT, AST and increased GSH concentration significantly in comparision with extract-untreated group. + The HPLC-DAD method was validated for the qualitative and quantitative determination of major bioactive compound, arborinine. The result showed that content of arbornine in dried material and preparations were 0.011 and 0.096%, respectively. + Quality standards of preparations from this species were improved.   
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