Project's information

Project's title Fabrication the titannitrid combining with nanostructured hydroxyapatite biomedical coating on stainless steel substrate, applying for splints and screws in medicine
Research hosting institution Institute for Tropical Technology
Project leader’s name Assoc. Prof. Dr. Dinh Thi Mai Thanh
Project duration 01/01/2011 - 01/01/2012
Project’s budget 450 million VND
Classify Excellent
Goal and objectives of the project
  • Fabrication the titannitrid film on 304 and 316L stainless steel substrate, testing mechanical property and biocompatibility in simulated body fluid solution.
  • Fabrication the coating combining titannitrid and hydroxyapatite (HAp) to enhance bioactivity and limit corrosion of titannitrid implant material, apply in orthopedics and dentistry.
Main results

Theoretical results:

  • Successful synthesis of the nanosized titannitrid film on 304/ and 316L stainless steel substrate by vacuum arc spraying method.
  • Successful preparation of hydroxyapatite coating on titannitrid coated 316L stainless steel by potential applied method.
  • Study of biocompatibility of TiN/316L stainless steel, HAp/TiN/316L stainless steel in simulated body fluid solution.

Applied results: The project has initially indicated application of HAp/TiN/316LSS material for splints and screws in orthopedics.

Novelty and actuality and scientific meaningfulness of the results
  • Successful study on the synthetic conditions of TiN film.
  • Investigation effect of some factors such as: solution composition, temperature, applied potential, synthetic time on HAp coating electro-deposition process.
  • The biocompatibility results of TiN/316LSS and HAp/TiN/316LSS showed that HAp coating synthesized by electrodeposition had shielding ability for substrate. 
Products of the project

Scientific papers

  • Scientific papers in referred journals and is waiting published (list):
  1. Pham Thi Nam, Dinh Thi Mai Thanh, Nguyen Thu Phuong, Nguyen Thi Thu Trang, Thai Hoang, Investigation of factors affecting on the electrodeposition process of hydroxyapatite coating on 304 stainless steel substrate, Journal of Science and Technology 49 (5A) (2011) 114-121.
  2. Pham Thi Nam, Didier Devilliers, Tran Dai Lam, Nguyen Thu Phuong, Dinh Thi Mai Thanh, Electrochemical behavior of 316L stainless steel in simulated body fluid solution, Vietnam Journal of Chemistry 50(6B) 99-105.
  3. Nguyen Thu Phuong, Pham Thi Nam, Đinh Thi Mai Thanh. Research corrosion of TiN/316L stainless steel in Ringer Lactate solution, Journal of Science and Technology, 2011, 6B, xxx-xxx.
  4. Pham Thi Nam, Nguyen The Huyen, Tran Dại Lam, Dinh Thi Mai Thanh, Study on the electrochemical behavior of HAp/316L stainless steel materials in solution simulated body fluid. Vietnam Journal of Chemistry 50(6) (2012) 699-703.
  5. Dinh Thi Mai Thanh, Pham Thi Nam, Nguyen Thu Phuong, Le Xuan Que, Nguyen Van Anh, Thai Hoang, Tran Dai Lam. Controlling the electrodeposition, morphology and structure of hydroxyapatite coating on 316L stainless steel. Materials Science and Engineering C, Vol. 33(4), 2013, 2037-2045.
  6. Pham Thi Nam, Pham Ngoc Hieu, Dinh Thi Mai Thanh. Study on the electrochemical behavior of HAp/TiN/316LSS materials in solution simulated body fluid. Accepted published in Vietnam Journal of Chemistry, 03/2013.
  7. Phạm Thị Nam, Dinh Thị Mai Thanh. Physicochemical characterics of the TiN/316L stainless steel materials deposited by DC magnetron sputtering. Participating in the Conference of IX Chemistry staff Science, 15/2/2013, Accepted published in the Vietnam Journal of Chemistry 04/2013.
  • Scientific papers scientific submitted (list):
  1. Dinh Thi Mai Thanh, Pham Thi Nam, Nguyen Thu Phuong, Ha Phuong Thu, Uong Van Vy, Le Ba Thang, Tran Dai Lam. The electrochemical behavior of TiN/316LSS material in simulated body fluid solution. Chemistry Letter 3/2013.

Technological products (describe in details: technical characteristics, place):

  • Process technology of preparation of TiN film on stainless steel substrate by vacuum arc spraying method.
  • Process technology of preparation of nanostructured HAp coatings.

Education of 2 bachelor, 1 master and 1 PhD student:

  • Nguyen Thi Anh Tuyet, Hanoi University of Education 2, practice in 2012.
  • La Tra My, Faculty of Chemistry, Hanoi University of Education 2, defended bachelor thesis in 2011.
  • Pham Ngoc Hieu, Faculty of Chemistry, Hanoi University of Education, defended master’s thesis in 2012.
  • Pham Thi Nam, Institute for Tropical Technology, Dr. Thesis (2010-2015).
Research region

Military Medical Academy 103

Recommendations

This is the novel project, process was conducted in laboratory scale, the obtained results from the project have many prospects for orthopedics. We hope to combine with Military Medical Academy in order to test the project’s product HAp/TiN/316L on animal body.