Project's information
Project's title | Studies on the scientific basis for making products supporting treatment of the renal calculus from leaves of Coffea arabica |
Research hosting institution | Institute of Chemistry |
Project leader’s name | Dr. Nguyen Quyet Tien |
Project duration | 01/01/2011 - 01/01/2012 |
Project’s budget | 400.000.000 VND |
Classify | Fair |
Goal and objectives of the project | - Isolation and chemical structural elucidation of 3–4 compounds from water extract of Coffea arabica leaves. |
Main results | - Eleven compounds were isolated from Coffea arabica leaves and chemical structures of 9 compounds among them were elucidated. Three compounds including caffeine, 3β-hydroxylup-12-ene-28-oic acid and ursolic acid show good bioactivities (diuretic effect, anti-HIV, anti-cancer ). |
Novelty and actuality and scientific meaningfulness of the results | - First time, the Coffea arabica leaves sample in Vietnam was studied on chemical composition and several remarkable bioactive compounds were isolated such as caffeine, 3β-hydroxylup-12-ene-28-oic acid and ursolic acid. |
Products of the project | - Scientific articles: |
Recommendations | Further studies are required to investigate the potent treating renal calculus patients in large amount with products CAFETASO, the semi-acute toxicity of the products CAFETASO from Coffea arabica leaves. So that, we propose a new project: “Study on technological process of manufucturing funtional foods supporting treatment of renal calculus patients from leaves of Coffea arabica L.)” and please help us executing this suggesting project. |