- Research on chemical composition of Alocasia odora K. Koch.
- Create a product could be inhibitor the enzyme xanthine oxidase (in vitro) and lowers uric acid in experimental mice (in vivo) to support the treatment of gout.

- Isolated and determined the structure of 07 compounds including: Alocasin A (AO1), Hyrtiosin B (AO2), β-sitosterol (AO3), β-sitosterol β-D-glucoside (AO4), Hyrtiosulawesine (AO5), myristic acid (AO6) and cis-p-hydroxycinamic acid (AO7) from the EtOAc and MeOH extracts of Alocasia odora K. Koch.
- Evaluating the inhibitory activity of XO enzyme, alpha glucosidase enzyme and NO product of extracts and compounds AO1-AO7. The test results showed that the alkaloids showed strong alpha glucosidase inhibitory activity with IC50 value from 5.25±0.32 to 29.59±3.7 µM, the inhibitory effect on XO enzyme was quite good with IC50 value from 44.34± 2.15 to 93.29±4.7 µM and moderate inhibitory effect on NO production with IC50 value 163.3±11.7 to 294.9±9.8 µM.
- Studied acute toxicity and uric acid lowering effect on experimental rats of product AO. The results showed that the dose level of 5000 mg/kg body weight did not cause death to experimental animals orally and the dose level of 500 mg/kg had the effect of lowering blood uric acid content by 26.31% compared with the disease model.
- A process has been developed to prepare AO product which is an alkaloid-rich mixture with 44.95% content, with XO enzyme inhibitory activity with an IC50 value of 18.56±1.2 µg/mL and basic standards for this product.

- For the first time, Alocasia odora K. Koch was evaluated for inhibitory activity of xanthine oxidase enzyme, alpha glucosidase enzyme and NO production in invitro model and uric acid lowering effect in invivo model. 

- 02 published articles
+ Nguyen Thi Thu Ha, Pham Minh Quan, Nguyen Van Tuyen, Nguyen Thanh Tra, Le Thi Tu Anh, Ninh The Son, 2022, Chemcial Constituents of Alocasia odora Rhizomes and Their Biological Activities: Experimental and Molecular Docking Approaches. Revista Brasileira de Farmacognosia, 32: 819–826. doi: 10.1007/s43450-022-00318-x
+ Nguyen Thi Thu Ha, Nguyen Van Tuyen, Ninh The Son, Nguyen Thanh Tra, Le Thi Tu Anh, Nguyen Thi Thuy Linh, Pham Minh Quan, Le Thi Hai Yen, Nguyen Van Du, 2023, Phytochemical investigation and antimicrobial activity from rhizomes of Alocasia odora K. Kock. Journal of Science and Technology, 61(5), 780-787. doi: 10.15625/2525-2518/17303
- 01 utility solution:
+ Nguyen Thi Thu Ha, Nguyen Van Tuyen, Ninh The Son, Nguyen Thanh Tra, Le Thi Tu Anh, Process of extracting mixed alkaloids from Alocasia odora K. Koch. Number 3370, date 20/09/2023.
- Technological products (deposited in the Institute of Chemistry):
+ Botanical profile of Alocasia odora K. Koch.
+ Report on isolating and determining the structure of 07 compounds from the zhizomers of Alocasia odora K. Koch
+ Report on the inhibitory activity of xanthine oxidase enzyme, alpha glucosidase enzyme, inhibiting NO production of extracts and isolated compounds.
+ Report on the process of making AO product with a scale of 1kg/batch and evaluate the content of main active compounds.
+ Report on development of baseline standards for AO product.
+ Report on acute toxicity results and lowers uric acid in experimental mice.
+ 50 g of AO product.

We would like to propose Vietnam Academy of Science and Technology and Institute of chemistry to continously support us in developing these compounds for pharmaceutical industries to produce a medication product in order to strengthen public health.